Monday 17 April 2023COVID-19 after two years: trajectories of different components of mental health in the Spanish population
Epidemiology and Psychiatric Sciences
Our study aimed to identify trajectories for different components of mental health during a two-year follow-up of the COVID-19 pandemic, contextualizing them according to pandemic periods. We investigated the associations between mental health trajectories and various exposures, determining if differences existed among different mental health outcomes regarding these associations. We identified three latent trajectories for the studied outcomes, distinguishing between 'resilient' and 'chronic-worsening.' Overall, global health, cognitive health, and coping strategies were identified as common protective factors. Our results support heterogeneity in reactions to the pandemic and the need to study different mental health components over a longer follow-up. Understanding modifiable protective and risk factors associated with these trajectories would allow targeted interventions for specific population segments.
- Mental health
Monday 13 March 2023Purpose in life promotes resilience to age‑related brain burden in middle‑aged adults
Alzheimer's Research & Therapy
The study aimed to identify modifiable factors that promote cognitive resilience in middle age. The role of "purpose in life" (PiL) was investigated in 624 middle-aged adults. Although no differences were found in neuropsychological status or white matter lesion burden between PiL groups, it was discovered that in the lower PiL group, a greater number of white matter lesions had a negative impact on executive functions. Additionally, individuals with a higher sense of purpose in life displayed greater functional integration of the dDMN brain network, which was positively related to cognitive performance. These findings suggest that a greater sense of purpose in life may promote resilience against observable brain changes in middle age and improve cognitive function.
Thursday 15 December 2022Associations between repetitive negative thinking and resting-state network segregation among healthy middle-aged adults
Frontiers in Aging Neuroscience
The study examines the relationship between Repetitive Negative Thinking (RNT), which encompasses negative thoughts about the future and past, and the segregation of brain networks in middle-aged adults. Using resting-state functional magnetic resonance imaging, the study investigated the Anterior Salience Network (ASN), Default Mode Network (DMN), and Executive Control Network (ECN). Results indicate that RNT is associated with depression, emotional stability, cognitive complaints, and the segregation of the left Executive Control Network (LECN) and ASN. Additionally, the ventral DMN (vDMN) exhibits increased connectivity with the ASN and decreased connectivity with the LECN in relation to RNT. These findings suggest that higher levels of perseverative thinking are linked to increased segregation of the LECN and reduced segregation of the ASN, potentially contributing to poorer cognitive control and increased self-referential processes in RNT.
- Mental health
Saturday 20 August 2022Functional brain connectivity prior to the COVID-19 outbreak moderates the effects of coping and perceived stress on mental health changes. A first year of COVID-19 pandemic follow-up study
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging (2022)
The COVID-19 pandemic provides a unique opportunity to investigate the psychological impact of a global major adverse situation. Our aim was to examine, in a longitudinal prospective study, the demographic, psychological, and neurobiological factors associated with interindividual differences in resilience to the mental health impact of the pandemic.
- Mental health
Monday 28 March 2022Sense of Coherence Mediates the Relationship Between Cognitive Reserve and Cognition in Middle-Aged Adults
Frontiers in Psychology (2022)
In recent years, supported by new scientific evidence, the conceptualization of cognitive reserve (CR) has been progressively enriched and now encompasses not only cognitive stimulating activities or educational level, but also lifestyle activities, such as leisure physical activity and socialization.
Friday 11 November 2022Coffee Brains 6: Guttmann Cognitest: oportunidades de detección precoz del deterioro cognitivo
Friday 21 October 2022Coffee Brains 5: Cómo promover la resiliencia en el dolor crónico
Thursday 22 September 2022Coffee Brains 4: El cerebro eléctrico y la neuroestimulación