500 volunteers have already done the face-to-face tests at the Institut Guttmann

Five hundred volunteers of those who were selected to participate in the face-to-face phase of the project have already done the evaluations in person in Institut Guttmann and the Hospital Clínic. The rest of the volunteers who have not yet done the tests are expected to do them through this year.

These tests, which began in June 2018, provide detailed information on brain function and include a medical examination, physical evaluation, collection of biological samples, cognitive assessments, structural and functional brain magnetic resonance, electroencephalography and brain stimulation. Non-invasive based on the disturbance of brain activity.

Follow-up of the cohort

On the other hand, the online follow-up phase of the 5,000 targeted volunteers is still under way with new questionnaires that are sent out over the months.

The online phase is very important to continue having data on functionality, subjective complaints, habits, etc. In this way we have better correlations between neurobiological data and lifestyles, “explains Álvaro Pascual-Leone, scientific director of the study.



Analysis of data

Researchers have already analyzed the data of some 3,000 participants who have completed all the online questionnaires two years after the kick off of the project.

“The most remarkable thing that we have learned is that the aspects of daily life that are more important, more essential to keep the brain healthy, are social relationships, not feeling alone, feeling supported, and having a well-defined vital purpose, “says Pascual-Leone.

In fact, according to the data collected, the vital purpose, that is, knowing what one wants to achieve that transcends oneself, is so important that it mediates the effect of the rest.

“One can eat less, or worse, or not exercise, or exercise less, if it is because of a well-defined life purpose,” adds Pascual-Leone.


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